NGS in DNA Diagnostics Course

Course date: 11 September 2017 - 13 September 2017
Location: Erasmus MC

Click here for details of programme
Click here to register for this course
Click here for abstracts/reviews in preparation of the course


VKGL/VKGN ‘NGS in DNA diagnostics’ is a course aimed at Genomic Resequencing in a Medical Diagnostic Context, i.e to apply Next Generation Sequencing data as diagnostic tool in the hospital. Lectures will be accompanied with hands-on exploration.



The course is a joint effort from individuals of the "Nederlandse Vereniging voor Klinische Chemie”,  NVKC (18 points).

Program Outline 
  • Day 1 consists of an introduction to NGS techniques followed by specialised lectures on sample preparation, enrichment technologies and read mapping.
  • Day 2 will continue with lectures on variant calling, annotation and interpretation with a diagnostic emphasis applied to Gene Capturing Panels, Exome Screening and CNV analysis.
  • The afternoon of Day 1 & Day 2 is reserved for workshops and software demonstrations. Real data will be used where possible in hands-on tutorials using both commercial and open source software.
  • Day 3 focuses on impact of results in the lab and ethical and legal issues of NGS in the clinical application. Real-life applications of NGS in the clinic will be presented. A forum discussion between researchers and clinicians about mutual expectations, ethics, implications of NGS on diagnostics and data sharing concludes the day.

    Target audience
    This course is intended for bioinformaticians, researchers and molecular & clinical geneticists. The mixed programme will appeal to all those requiring a solid background in the application of NGS techniques for (routine) genetic diagnosis of a patient. The course will be mainly in English.

    Organisation and Registration

    The course is a joint effort from individuals of the NVHG/VKGL/VKGN (diagnostic) community of The Netherlands.  


    This course including self-study is 1,0 ECTS.

    Course material

  Date and Location
  • The course will be held at the Erasmus Medical Centre, Medical Faculty, at the 'Onderwijscentrum' and computer room C00-6

    • The course will start in lecture room: OWR-23
    • Three computers will be used on Tuesday and Wednesday afternoon (t.b.a.)

    See here for maps of the Erasmus MC, including the Educational centre:

     Registration fees

    • €250 for PhD students (€200 for 2 days)
    • €500 for researchers at universities or non-profit research institutes (€400 for 2 days)
    • €1000 for researchers from profit organizations (industry) (€800 for 2 days)
    • The fee for all other participants is: €500 (€400 for 2 days)

    Additional remark: AIOs are not considered PhD-students and will thus also not receive the reduced PhD-fee.

     PAYMENT: MGC Notification

    The Erasmus/LUMC Research School MGC has made a selection of courses it deems fit for its members. This course is not one of them.

    Therefore, the Erasmus/LUMC Research School MGC will not pay for its members to participate in this course. All MGC-members will need to pay themselves (or from personal budget) after receiving an invoice (please provide personal address) or will have their research departments pay for them (in that case, please provide ‘kostenplaatsnummer’ of the research group). To see if you are an MGC-member, here you can find an overview of all MGC research groups:  

    General information

    Financial regulation of the Postgraduate School MolMed

    From January 1st, 2017 the following financial rules apply, but they may differ per course still. Look at the course fee of each course to be sure which discounts are really applied:

    Non-commercial course, symposium or workshop fee: €200/day, €750/week

    • Participants of the postgraduate school MolMed: discount of 100%

    • However, the Research Management course and the workshops Photoshop/Illustrator/Indesign have to be paid from the ‘personal budget’ of employees, MolMed members and PhD students included. So they will receive an invoice from us which you have to pay and which will be reimbursed by your Department. When you will pay from your personal budget you need to provide us your home address details for the invoice

    • PhD students and Master’s students, regardless of institution: discount of 50%.

    • The course fees of research master’s students will be paid by their master program at rate of €100/ECTS. For not I&I master students: please inform your master program in advance whether they agree to pay.
    • Master’s students who are paying the fee from their private budget: discount of 75%. When you will pay from your personal budget you need to provide us your home address details for the invoice.
    • However, 2 courses in statistics are paid centrally by the Dept. of Research policy for all PhD students from Erasmus MC! These are R and the SPSS course. So for Erasmus MC PhD students, these courses are always free, provided you are officially registered as a PhD student.

    There is one fee for the entire course. There is no reduction for partial participation.

    Some courses have less course days: SPSS 3 days, Survival Analysis 2 days, Management 2 days, Presenting 1,5 days and also other may be shorter as indicated on the website.

    Commercial participants, companies & sponsors are invited to inquire about commercial tuition fees and about sponsoring.

    All invoices will be sent by email to the mail address that you filled in upon registration. If this address is not correct we use your Erasmus MC address.

    Those who register for a course, symposium or workshop agree with these financial conditions. 




Click here for details of programme
Click here for Abstracts/reviews in preparation of the course (available soon!)
Click here to register for this course

Click here for the other items