SNP Course XV: SNPs and Human Diseases

Course date: 12 November 2018 - 16 November 2018
Location: Erasmus MC, Ae-4.06

Click here for details of programme
Click here to register for this course
Click here for abstracts/reviews in preparation of the course

Attached you will find the program of the course

The analysis of DNA variations, including Single Nucleotide Polymorphisms (SNPs), is a standard research approach to understand causes of disease, in particular the so-called "complex” diseases such as diabetes, osteoporosis, cancer, Alzheimer disease, etc. The field is changing fast with large scale projects (Human genome, dbSNP, HapMap, 1000genomes, ENCODE) and novel technology being continuously introduced, including Next Generation Sequencing.

The aim of this course is to give a broad introduction in SNP techniques and applications. The course is primarily organized for PhD students and postdocs of the Erasmus Postgraduate School Molecular Medicine, Nihes, MGC and other research schools. Other participants, e.g., scientists, students, and technicians from other universities in- and outside Netherlands are also welcome. The total number of participants is limited to 75. 

This is an advanced course on complex genetics. While there is some overlap in content, the SNP course offers more than the NIHES-ESP 57 course in the Erasmus Summer Program. It is recommended for the participants of the SNP course to have basic knowledge of the central molecular biological dogma's (such as DNA and gene structure, DNA encodes RNA encodes protein, etc.) and of basic genetic principles. So you should have attended the course ’Genetics for Dummies’, organised also by MolMed, or this years’ NIHES Summer program Genetic Epidemiology.

Monday 12 November
Tuesday 13 November
Wednesday 14 November
Thursday 15 November
Friday 16 November

Room Ae-4.06 (lecture)
Room OWR-16 (practical)

Full participation in this course will be rewarded with 2,0 ECTS.

Basic background knowledge can also be found in any decent textbook of human molecular biology and genetics, such as "Molecular Biology of the Cell" (5th ed.; editors: Alberts et al.; published by Garland Sciences) and "Human Molecular Genetics" (4th ed.; editors Strachan & Read; published by Garland Sciences; £40,-). To this aim, also a series of basic papers is published on our website: on the course page. At the start of the course a comprehensive reader will be issued. 

Presentations by selected participants
All participants will be requested to send a short presentation or description of their own research and field of interest in advance to the course organisation (email to: In this way we get to know your research topics, to better prepare the topics of the course. All participants are expected to prepare some overhead sheets. A selection of the candidates will be asked to present their own research topics on the 1st course day, Monday.

On the first 4 days "learning-by-doing” sessions ("practicals”) on the bio-informatic and statistical analysis in this field are organised. On the last 2 days, our ‘special guests’ as key note speakers are scheduled. Subscription is now open on: 

Attendance fees
The subscription fee of non-commercial participants for the 5-day course is € 750. Discounts are handled as followed:
• All PhD and research master students docs get a discount of 50% and pay €375,50.
• All participants from the postgraduate school MolMed get a discount of 100% and pay €0. 
• Master students who pay the fee themselves get a discount of 75% and pay €187,75. When you will pay this course of your "persoonlijk budget" (PB) you need to provide us your personal address details

If these financial requirements pose a problem but you wish to attend the Course, please contact Frank van Vliet, managing director of the Erasmus Postgraduate School Mol Med, at:

PAYMENT: MGC Notification

The Erasmus/LUMC Research School MGC has made a selection of courses it deems fit for its members. This course is not one of them.

Therefore, the Erasmus/LUMC Research School MGC will not pay for its members to participate in this course. All MGC-members will need to pay themselves (or from personal budget) after receiving an invoice (please provide personal address) or will have their research departments pay for them (in that case, please provide ‘kostenplaatsnummer’ of the research group). To see if you are an MGC-member, here you can find an overview of all MGC research groups:

Click here for details of programme
Click here for Abstracts/reviews in preparation of the course (available soon!)
Click here to register for this course

Click here for the other items