SNP Course XVII: SNPs and Human Diseases

Course date: 16 November 2020 - 19 November 2020
Location: Online

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Nb. attached program of the course.

SNP Course XVII: SNPs and |Human Diseases  
Course Faculty: Local (André Uitterlinden, Joyce van Meurs, Annemieke Verkerk, Linda Broer, Robert Kraaij, Fernando Rivadeneira & Frank van Vliet) + many invited top-speakers, also from abroad.

The analysis of DNA variations, including Single Nucleotide Polymorphisms (SNPs), is a standard research approach to understand causes of disease, in particular the so-called "complex” diseases such as diabetes, osteoporosis, cancer, Alzheimer disease, etc. The field is changing fast with large scale reference projects (dbSNP, HapMap, 1000genomes, ENCODE), very large biobanks (UK Biobank, MVP), global collaboration in consortia, and novel technology being continuously introduced and refined, including SNP array genotyping and DNA  Sequencing. Several aspects are now being explored for implementation in clinical settings, such as for DNA diagnostics and risk profiling with polygenic risk scores.

The aim of this course is to give a broad introduction in SNP techniques and applications. The course is primarily organized for PhD students and postdocs of the Erasmus Postgraduate School Molecular Medicine, Nihes, MGC and other research schools. Other participants, e.g., scientists, students, and technicians from other universities in- and outside Netherlands are also welcome. The total number of participants is limited to 50.The attendance fee of the 4-day course is €600, but some participants can get a discount. See below for all details.

Please note: This year the entire course is digital. All talks will be 35 minutes with 10 minute discussion time.

This is an advanced course on genetics on the latest advances in complex traits and monogenic conditions. Participation in the Genetic and Molecular Epidemiology courses organized by NIHES during the Erasmus Summer Program (ESP-43, ESP-57 & ESP-74) is not a pre-requisite but is highly recommended. Participants of the SNP course should have basic knowledge of molecular biology (such as DNA and gene structure, DNA translation to protein, etc.) and basic principles of techniques used for gene discovery. Participants lacking this knowledge should attend the course ’Genetics for Dummies’, organised by MolMed before the course.

Basic background knowledge can also be found in any decent textbook of human molecular biology and genetics, such as "Human Molecular Genetics" (5thed.; editors Strachan & Read; published by Taylor & Francis Inc.; €75,27). To this aim, also a series of basic papers will be published on our website: www.molmed.nlon the course page. At the start of the course a comprehensive list of recommended literature will be issued.

On the first 3 days "learning-by-doing” sessions ("practicals”) on the bio-informatic and statistical analysis in this field are organised. Every day will end with a masterclass. The last day will have multiple masterclasses in the afternoon.

Audience and participation
The course is organized for all academic levels and for all scientific backgrounds, but is somewhat advanced and requires background knowledge of the central molecular biological dogma's (e.g., DNA- and gene-structure, DNA encodes RNA encodes protein, etc.) and of basic genetic principles. Those who have not such knowledge, are strongly advised to first follow the introductory course ’Genetics for Dummies’, organized also by MolMed, or the NIHES-ESP 57 course (Genomics in Molecular Medicine).

We welcome all academic levels including professors, senior scientist, PhD students, postdocs, and technicians, clinicians as well as basic scientists, and from all scientific disciplines (from medicine to biology, and epidemiology, psychology to economics). The course is open to all scientific institutes in- and outside the Netherlands, such as the Erasmus MC Postgraduate School Molecular Medicine, NIHES, and MGC, and other research schools, as well as for other universities in- and outside the Netherlands.

Local (André Uitterlinden, Joyce van Meurs, Annemieke Verkerk, Linda Broer, Robert Kraaij, Fernando Rivadeneira) + many invited top-speakers, also from abroad.

Date, Time & Location
Monday 16 November - Thursday 19 November
Online (Zoom or Teams, t.b.a.)

Full participation is  2,0 ECTS.


Course fees 
For non-commercial participants the course fee  € 600/ 4 days
PhD students get a 50% discount and pay €300/ 4 days. 
Participants from the postgraduate school MolMed get a 100% discount and pay €0.
Master students, get a 50% discount and pay €300/ 4 days. 
Master students who have to pay the fee from their personal budget get a 75% discount and pay €150/ 4 days. 
If these financial requirements should pose a problem, please contact Frank van Vliet, managing director of the Erasmus Postgraduate School Mol Med, at:

General information
Financial regulation of the Postgraduate School MolMed, from January 1st 2019, the following financial rules apply, but they may differ per course still. Look at the course fee of each course to be sure which discounts are really applied:
• Non-commercial course, symposium or workshop fee: €200/day, €750/week
• Participants of the postgraduate school MolMed: discount of 100%
• However, the Personal Leadership course and the workshops Photoshop/Illustrator/Indesign have to be paid from the ‘personal budget’ of employees, MolMed members and PhD students included. So they will receive an invoice from us which you have to pay and which will be reimbursed by your Department. When you will pay from your personal budget you need to provide us your home address details for the invoice. 
If there is no personal budget left, the MM-members get a discount of 100%.
• PhD students and Master’s students, regardless of institution: discount of 50%.
•The course fees of research master’s students will be paid by their master program at rate of €100/ECTS. For not I&I master students: please inform your master program in advance whether they agree to pay.
•Master’s students who are paying the fee from their private budget: discount of 75%. When you will pay from your personal budget you need to provide us your home address details for the invoice.
•However, 2 courses in statistics are paid centrally by the Dept. of Research policy for all PhD students from Erasmus MC! These are R and the SPSS course. So for Erasmus MC PhD students, these courses are always free, provided you are officially registered as a PhD student.
There is one fee for the entire course. There is no reduction for partial participation.
Commercial participants, companies & sponsors are invited to inquire about commercial tuition fees and about sponsoring.
All invoices will be sent by email to the mail address that you filled in upon registration. If this address is not correct we use your Erasmus MC address.
Those who register for a course, symposium or workshop agree with these financial conditions.

Click here for details of programme
Click here to register for this course

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